FOXA1 Expression in Breast Cancer—Correlation with Luminal Subtype A and Survival

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FOXA1 expression in breast cancer--correlation with luminal subtype A and survival.

PURPOSE FOXA1, a forkhead family transcription factor, is essential for optimum expression of approximately 50% of estrogen receptor alpha (ERalpha):estrogen responsive genes. FOXA1 is expressed in breast cancer cells. It segregates with genes that characterize the luminal subtypes in DNA microarray analyses. The utility of FOXA1 as a possible independent prognostic factor has not been determin...

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ژورنال

عنوان ژورنال: Clinical Cancer Research

سال: 2007

ISSN: 1078-0432,1557-3265

DOI: 10.1158/1078-0432.ccr-07-0122